One session lasts three to four months. The drop in oil and the tightening of pores are felt first, with smoother texture following a little later. Because a diluted dose goes into a shallow layer, the effect is gentler than botulinum placed in muscle, and repeating keeps the settled state going.

Because a small amount goes into a shallow layer of skin rather than into muscle, expression is barely affected. The drug is diluted and spread widely, so it never gathers in one place enough to weaken it. Small red marks remain for a while where the needle went in, so avoid make-up on the day.

Oil drops and pores tighten over one to two weeks, because it takes time to act on the oil glands and the muscles that raise the hairs. Rather than targeting one spot, it is spread evenly across the whole face to smooth the texture, so the change shows across the face as a whole.